google-deepmind/alphagenome_research v0.3.0

v0.3.0

Repository: google-deepmind/alphagenome_research

Tag: v0.3.0

Published: 2026-07-14T14:49:10Z

Prerelease: no

Release notes:

Added

• Support indel stitching in AlphaGenome variant prediction and enable it by

default.

• Support calculating variant score quantiles.
• Export .pyi files for generated protocol buffers.

Changed

• Improvements for fine-tuning (per-head loss weights, target smoothing,

splicing ROPE initialization and BatchNorm training mode)

• Migrate to use FastaExtractor from alphagenome.
• Use variant.start to calculate the middle of the center mask.
• Fix negative strand bug for score_interval and score_variant.
• Update type annotations and fix typing errors.